Recent article discusses the possibility of using phages versus COVID-19, since no drug has been effective against coronavirus.
The COVID-19 pandemic has overwhelmed health systems, putting staff under stress and bringing unprecedented challenges to the economy and social life . At least the 15% patients with COVID-19 have a serious illness, so effective treatment is desperately needed. The international scientific community has been involved in many studies to find drugs to treat the disease and there are reports suggesting the potential efficacy of some actors. However, it should be emphasized that although many drugs have in vitro activity against different coronaviruses, currently no clinical evidence supports the efficacy and safety of any drug in humans . At the same time, progress in clinical research is threatened as the pandemic closes drug research for many other diseases, including cancer, Where, as some experts believe, clinical studies have been reduced to almost zero . In this extreme situation, reuse of medicines may be the right strategy to seek a rapid therapeutic response and, hopefully, effective at the COVID-19 pandemic. A good example of such a strategy is the current enthusiasm for reusing metformin, a well-known drug used to treat type diabetes 2, for cancer prevention and treatment . There have also been attempts to reuse metformin for cardiovascular disease , and even for bacterial infections .